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kash koi mil jaye faadu mp3 kash koi mil jaye faadu mp3 .Flow-induced dilatation of the brachial artery in an independent and random sample of healthy men and women.
Physiologic mechanisms regulating the diameter of arteries are essential in understanding the relations between peripheral arterial disease and cardiovascular disease. The purpose of this study was to determine the effects of flow and gender on flow-induced dilatation (FID) of the brachial artery in healthy humans. Twenty-two healthy volunteers (six men, 16 women, aged 21 to 37 years), without known disease, who were not taking medications, underwent simultaneous FID and assessment of endothelial function of the brachial artery using high-resolution ultrasound in both arms. FID was measured after occlusion of the brachial artery and hyperemic response to a standard endothelium-dependent vasodilator (glyceryl trinitrate, GTN), an endothelium-independent dilator (sodium nitroprusside, SNP), and a mixture of both (GTN/SNP). Arterial diameter and blood flow velocity were determined at rest and during maximal vasodilation. The gender difference was noted in that men had higher brachial artery diameter than did women (4.5 +/- 0.1 mm vs 3.8 +/- 0.1 mm, P =.009). Flow-mediated dilation of the brachial artery was similar in men and women (17.4 +/- 3.4% vs 24.1 +/- 6.6%; P =.19). However, FID of the brachial artery after SNP was significantly higher in women than men (33.1 +/- 5.6% vs 19.3 +/- 7.0%; P =.004). Furthermore, FID of the brachial artery after GTN/SNP was significantly lower in men than in women (12.9 +/- 3.8% vs 24.3 +/- 4.8%; P =.02). In addition, FID of the brachial artery after SNP was significantly correlated with age (r = -0.51, P =.03) but there was no 0b46394aab